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Compound research

What role does NAD+ play in laboratory research?

NAD+ is a redox coenzyme and metabolic substrate involved in many cellular processes. These broad reviews explain the biochemical context; they are not claims that adding exogenous NAD+ produces a particular human outcome.

View NAD+Check batch records
Research compoundNAD+
CAS number53-84-9
Molecular formulaC21H27N7O14P2
Molecular weight663.43 g/mol

Source trail

Selected references

  1. Scientific review

    NAD(+) metabolism and its roles in cellular processes during ageing.

    Covarrubias AJ, Perrone R, Grozio A, et al. Nature Reviews Molecular Cell Biology (2021).

    Reviews NAD+ metabolism and its roles in cellular processes.

    PMID 33353981 · DOI 10.1038/s41580-020-00313-x

  2. Scientific review

    NAD+ and sirtuins in aging and disease.

    Imai S, Guarente L. Trends in Cell Biology (2014).

    Explains the biochemical relationship between NAD+ availability and sirtuin activity.

    PMID 24786309 · DOI 10.1016/j.tcb.2014.04.002

How to interpret this page

These sources establish research context only. They do not verify an Astral lot, support dosing or human use, or prove safety or efficacy. Use the lot-specific COA for analytical evidence.

Editorially curated and source-verified; not independently peer-reviewed by Astral. Last source check: 2026-07-21. Read the editorial policy.